描述：Identity:Histidyl tRNA synthetase, HisRS, histidine translase.Source Material:Bovine thymus (New Zealand origin).Clinical Indications:Autoantibodies present in polymyositis, dermatomyositis.Ordering I
AROTEC_Jo-1_MSDS.pdf
Version/Date: B/04.05.26
MATERIAL SAFETY DATA SHEET
Product: Jo-1 antigen, from bovine thymus
Synonym: Histidyl-tRNA Synthetase / Histidine-tRNA Ligase / HISRS
E.C. No.: 6.1.1.21
CAS Registry No.: not available
Catalog No.: ATJ01-02, ATJ01-05, ATJ01-10
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Page 1 of 3
AroTec Diagnostics Limited, 10 Hutt Road, Petone, P.O. Box 38586 Wellington Mail Centre, Wellington 6332, New Zealand
+64-4-5690361 ¬ +64-4-5690366 : info@arodia.com
Composition Information
Chemical Formula/Composition: N/A
Physical Description: Clear, colourless liquid/frozen liquid
Stability/Reactivity: Stable. Hazardous decomposition or polymerization will not occur.
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Hazard Identification（s）
Hazards identified with this product are those associated with the following component（s）:
Glycerol, DNase, RNase and Protease free
CAS Registry No.: 56-81-5
Concentration: 20% v/v
Potential Health Effects:
Eye: May cause mild eye irritation.
Skin: May cause mild skin irritation. Low hazard for usual laboratory handling.
Ingestion: May cause gastrointestinal irritation with nausea and diarrhoea. May cause
headache. Expected to be a low ingestion hazard.
Inhalation: Low hazard for usual laboratory handling. Inhalation of mist of this material
may cause respiratory tract irritation.
Chronic: May cause kidney injury.
Potential hazards identified with this product are those associated with the title component
（Jo-1 antigen） and with following buffer and stabilising components present at concentrations
at which they are not normally considered to be hazardous:
Component CAS Registry No. Concentration
4-（2-Hydroxyethyl）-1-piperazineethanesulfonic acid
（HEPES）
7365-45-9 <0.5%
Phenylmethylsulfonylfluoride 329-98-6 <0.002%
Dithiothreitol 3483-12-3 <0.005%
Micr-O-protect 64-17-5
30007-47-7
2612-54-3
0.1% AROTEC_Jo-1_MSDS.pdf
Version/Date: B/04.05.26
MATERIAL SAFETY DATA SHEET
Product: , from bovine thymus
Synonym: Histidyl-tRNA Synthetase / Histidine-tRNA Ligase / HISRS
E.C. No.: 6.1.1.21
CAS Registry No.: not available
Catalog No.: ATJ01-02, ATJ01-05, ATJ01-10
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Page 2 of 3
AroTec Diagnostics Limited, 10 Hutt Road, Petone, P.O. Box 38586 Wellington Mail Centre, Wellington 6332, New Zealand
+64-4-5690361 ¬ +64-4-5690366 : info@arodia.com
Toxicological Information:
Toxicological properties have not been fully investigated. May be harmful by ingestion,
inhalation or skin contact. May cause allergic or autoimmune reactions.
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Storage and Handling
Store according to instructions on product and/or package insert.
Avoid contact with material. Wear protective equipment （protective clothing, chemicalresistant gloves, eye protection, respiratory protection） when handling.
Spill or Release of Material:
Wear protective equipment.
Absorb liquid on dry sand, diatomite, vermiculite or other drying agent and place in closed
container for disposal.
Ventilate area and wash spill site after material absorption is complete.
Waste Disposal:
Incinerate or landfill as complies with state and local laws for biological materials.
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First Aid Procedures
Substance in Contact with Skin:
Remove contaminated clothing and rinse with copious amounts of soap and water for a
considerable amount of time. Seek medical aid if irritation develops or persists.
Substance has been Swallowed:
If victim is conscious rinse mouth several times with water, do not swallow. Call a physician or
take victim to hospital.
Substance in Contact with Eyes:
Rinse with copious amounts of water for a considerable time. Seek medical aid if irritation
develops or persists.
Substance has been Inhaled:
Take victim into the fresh air and allow to rest. Call a physician or take victim to hospital.
Additional Instructions:
Observe proper laboratory instructions when handling this material.
***************************************************************************************** AROTEC_Jo-1_MSDS.pdf
Version/Date: B/04.05.26
MATERIAL SAFETY DATA SHEET
Product: , from bovine thymus
Synonym: Histidyl-tRNA Synthetase / Histidine-tRNA Ligase / HISRS
E.C. No.: 6.1.1.21
CAS Registry No.: not available
Catalog No.: ATJ01-02, ATJ01-05, ATJ01-10
*****************************************************************************************
Page 3 of 3
AroTec Diagnostics Limited, 10 Hutt Road, Petone, P.O. Box 38586 Wellington Mail Centre, Wellington 6332, New Zealand
+64-4-5690361 ¬ +64-4-5690366 : info@arodia.com
Fire Fighting Measures
General Information
Structural fire-fighting gear and self-contained breathing apparatus will provide adequate
protection if this product is in a fire area.
Extinguishing Media
In case of fire use water spray, dry chemical, carbon dioxide, or chemical foam.
Unusual Fire and Explosion Hazards
N/A
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Disclaimer
The information provided in this Material Safety Data Sheet is furnished in good faith and
without warranty of any kind. Personnel handling this material must consider these data only
as supplemental to other information gathered by them and must make independent
determinations of the suitability and completeness of information from all sources to assure
proper use and disposal of the materials and the safety and health of employees and
customers. AroTec Diagnostics Limited assumes no liability or responsibility resulting from the
use of, or reliance on, this information.
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