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          技術(shù)文章
          首頁 > 技術(shù)文章 > Vitronectin 16-16-220920

          Vitronectin 16-16-220920

           更新時間:2018-07-30 點(diǎn)擊量:1550

           

           

           

           

          Athens Research & Technology自1986年以來一直在凈化人類蛋白質(zhì)和開發(fā)這些蛋白質(zhì)的多克隆抗血清。我們專注于高純度,高活性的人類蛋白質(zhì)。我們常規(guī)純化絲氨酸蛋白酶,蛋白酶抑制劑,中性粒細(xì)胞酶,載脂蛋白,脂蛋白,血小板蛋白,轉(zhuǎn)鐵蛋白,免疫球蛋白等。世界各地的研究人員已經(jīng)從我們這里購買了這些研究試劑超過二十五年。您將看到我們的產(chǎn)品在炎癥,冠心病,自身免疫性疾病,癌癥,阿爾茨海默病等研究的主要科學(xué)出版物中被引用。

          我們還從動物血清和組織中分離蛋白質(zhì)。

          我們的產(chǎn)品被診斷和制藥行業(yè)的先進(jìn)者用作體外診斷和免疫測定試劑盒的組分,以及細(xì)胞培養(yǎng)基,包括支持干細(xì)胞的培養(yǎng)基。雅典研究和技術(shù)的蛋白質(zhì)也被開發(fā)生物治療藥物的研究人員用于概念驗證研究。

           

          Vitronectin, Human Plasma

          玻連蛋白,人血漿

          產(chǎn)品編號:

          16-16-220920

           

          直接從制造商處購買。
          批量數(shù)量可用。

          MW:65,000和75,000 
          滅絕系數(shù):1.38

          從10mM磷酸鈉,pH7.7冷凍干燥


          玻連蛋白和纖溶酶原激活物抑制劑1型是在循環(huán)系統(tǒng)和細(xì)胞周圍區(qū)域相互作用以調(diào)節(jié)纖維蛋白溶解,細(xì)胞粘附和遷移的蛋白質(zhì)。纖溶酶原激活物抑制劑1型,絲氨酸蛋白酶,通過其與血漿蛋白質(zhì)玻連蛋白的結(jié)合,影響作為止血過程的關(guān)鍵調(diào)節(jié)劑的過程,例如血栓形成和傷口愈合。此外,玻連蛋白和纖溶酶原激活物抑制劑1型復(fù)合物在腫瘤轉(zhuǎn)移等事件中調(diào)節(jié)血小板和細(xì)胞與細(xì)胞外基質(zhì)的結(jié)合。玻連蛋白的血漿濃度為200至400μg/ ml。

          儲存:-20°C

          純度:SDS-PAGE約95%

          通過FDA批準(zhǔn)的測試,血漿制備顯示對HBsAg,抗-HCV,抗-HBc無反應(yīng),對抗-HIV 1和2呈陰性。

          雅典研究與技術(shù)產(chǎn)品是實(shí)驗室試劑,不得用于人體或用于任何藥物目的。僅供研究或進(jìn)一步制造使用。


          產(chǎn)品引用:
          Wihadmadyatami H,RöderL,BerghöferH,Bein G,Heidinger K,Sachs UJ,Santoso S.針對IIb3和v3的免疫接種,其中Glanzmann血小板癥的1型變體由錯義突變引起Gly540Asp在3. Thromb Haemost上。2016年8月1日; 116(2):262-71。doi:10.1160 / TH15-12-0982。Epub 2016年4月21日。

           

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