Athens Research & Technology自1986年以來(lái)一直在凈化人類(lèi)蛋白質(zhì)和開(kāi)發(fā)這些蛋白質(zhì)的多克隆抗血清。我們專(zhuān)注于高純度，高活性的人類(lèi)蛋白質(zhì)。我們常規(guī)純化絲氨酸蛋白酶，蛋白酶抑制劑，中性粒細(xì)胞酶，載脂蛋白，脂蛋白，血小板蛋白，轉(zhuǎn)鐵蛋白，免疫球蛋白等。世界各地的研究人員已經(jīng)從我們這里購(gòu)買(mǎi)了這些研究試劑超過(guò)二十五年。您將看到我們的產(chǎn)品在炎癥，冠心病，自身免疫性疾病，癌癥，阿爾茨海默病等研究的主要科學(xué)出版物中被引用。
我們還從動(dòng)物血清和組織中分離蛋白質(zhì)。
我們的產(chǎn)品被診斷和制藥行業(yè)的先進(jìn)者用作體外診斷和免疫測(cè)定試劑盒的組分，以及細(xì)胞培養(yǎng)基，包括支持干細(xì)胞的培養(yǎng)基。雅典研究和技術(shù)的蛋白質(zhì)也被開(kāi)發(fā)生物治療藥物的研究人員用于概念驗(yàn)證研究。
16-14-161820
MW：29,000
滅絕系數(shù)：1.0
在50mM MES中冷凍，pH 4.5，用700mM NaCl
蛋白酶3是位于多形核白細(xì)胞的azurophil顆粒中的絲氨酸蛋白酶之一。它已被鑒定為韋格納肉芽腫病的自身抗原，這是一種并發(fā)多形性細(xì)胞增生的系統(tǒng)性血管炎。
儲(chǔ)存：-70°C或更低
純度：通過(guò)SDS-PAGE> = 95％。
通過(guò)FDA批準(zhǔn)的測(cè)試，從全血制備顯示對(duì)HBsAg，抗-HCV，抗-HBc無(wú)反應(yīng)，對(duì)抗-HIV 1和2呈陰性。
雅典研究與技術(shù)產(chǎn)品是實(shí)驗(yàn)室試劑，不得用于人體或用于任何藥物目的。僅供研究或進(jìn)一步制造使用。
產(chǎn)品引用：
Towstyka NY，Shiromizu CM，Keitelman I，Sabbione F，et al。
中性粒細(xì)胞彈性蛋白酶對(duì)γδT細(xì)胞活化的調(diào)節(jié)作用。
免疫學(xué)。2017年9月9日doi：10.1111 / imm.12835。[提前打印]
Martin KR，Kantari-Mimoun C，Yin M，Pederzoli-Ribeil M，et al。蛋白酶3是一種磷脂酰絲氨酸結(jié)合蛋白，影響微泡的產(chǎn)生和功能。
J Biol Chem。2016年5月13日; 291（20）：10476-89。doi：10.1074 / jbc.M115.698639。Epub 2016年3月9日。
Schreiber A，Eulenberg-Gustavus C，Bergmann A，Jerke U，Kettritz R.
來(lái)自雙轉(zhuǎn)基因中性粒細(xì)胞方法的課程，用于在小鼠中誘導(dǎo)抗蛋白酶3抗體介導(dǎo)的血管炎。
J Leukoc Biol。2016年12月; 100（6）：1443-1452。Epub 2016年6月30日。
Barauskas O，et al。丙型肝炎病毒NS3蛋白酶抑制劑GS-9256和vedroprevir的結(jié)合動(dòng)力學(xué)，效力和選擇性。
Biochim Biophys Acta。2014年12月; 1840年（12）：3292-8。doi：10.1016 / j.bbagen.2014.08.002。Epub 2014年8月17日。
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